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Duloxetine has a central mechanism for suppressing the pain syndrome, manifested primarily by an increase in the threshold of sensitivity to pain in the syndrome of neuropathic pain.

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Duloxetine is used to treat depression and anxiety. In addition, Duloxetine is used to relieve nerve pain (peripheral neuropathy) in people with diabetes or persistent pain such as arthritis, chronic back pain or fibromyalgia (a condition that causes widespread pain). Duloxetine can improve mood, sleep, appetite and energy levels and reduce nervousness. It can also reduce pain due to certain conditions. Duloxetine is known as a serotonin and norepinephrine reuptake inhibitor (SNRI). This medication helps to restore the balance of some natural substances (serotonin and norepinephrine) in the brain. Buy Cymbalta Online | Cymbalta 60 mg | Duloxetine 60 mg


The recommended starting dose is 60 mg 1 once a day. If necessary, the daily dose can be increased from 60 mg to a maximum dose of 120 mg/day in 2 divided doses. In patients with severe renal impairment (CK <30 ml/min), the initial dose should be 30 mg once a day. In patients with hepatic impairment, reduce the initial dose or reduce the frequency of administration.

Side Effects:

From the central nervous system: often – dizziness (except vertigo), sleep disturbances (drowsiness or insomnia), headache (a headache was less common than the placebo group); sometimes – trembling, weakness, blurred vision, lethargy, fear, yawning; very rare: glaucoma, mydriasis, blurred vision, restlessness, disorientation. From the digestive system: often – dry mouth, nausea, constipation; sometimes – diarrhea, vomiting, decreased appetite, a change in taste, a violation of liver function; very rare – hepatitis, jaundice, high alkaline phosphatase, ALT, AST, and bilirubin; Belching, gastroenteritis, stomatitis.

Buy Cymbalta Online | Cymbalta 60 mg | Duloxetine 60 mg
Buy Cymbalta Online | Cymbalta 60 mg | Duloxetine 60 mg


Use during pregnancy is only possible if the intended use exceeds the potential risk to the fetus because the clinical experience of duloxetine during pregnancy is insufficient. If it is necessary to take the drug while breastfeeding, you must decide whether to stop breastfeeding (due to lack of experience). Patients should be advised that they should inform their physician from the beginning or plan their pregnancy during duloxetine.



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